3803 Parkwood Blvd, Suite 400, Frisco, TX 75034

 
Supreme Labs

HEREDITARY CARDIAC TEST

WHY GENETIC TESTING?

Supreme Medical Laboratories wants to help you preserve your body’s most vital organ, the heart.

How can we help you?

Supreme Medical Laboratories offers state-of-the-art genome sequencing through NGS and a comprehensive analysis, to target __ genes associated with __ inherited cardiac conditions. Our Hereditary Cardiac Test is intended to determine the chances that a healthy individual, with a family history of cardiac conditions, might develop a heart disease.

Why should I get tested?

Several heart diseases are caused by Dominant genes; meaning that if your first-degree relative has been diagnosed with a Hereditary Cardiac Disease, you pose a 50% chance of carrying the gene as well. While diet and lifestyles factor into the overall health of an individual’s heart, genetic influences make up a staggering 50% of risk for cardiac diseases. If you have a family history of cardiac complications, or simply want to take precaution measures, our Hereditary Cardiac Test was made for you

check_circleIn the United States someone has a heart attack every 34 seconds.

check_circleEvery 60 seconds someone dies from a heart disease related event.

check_circleCoronary Heart disease is the most common type of heart disease, killing 380,000 people annually.

check_circleThe Human Genome Project which saw the first human’s genome being sequenced was completed only 18 years ago and cost a staggering 3 billion dollars. This process laid the foundation for Next Generation Sequencing which was enhanced and made both cost and time efficient. In the past, Sequencing of the genome was only available for a very tiny exclusive portion of the population; Supreme Medical Laboratories makes it accessible to everyone.

check_circle• Every 60 seconds someone dies from a heart disease related event.

How does it work?

Advancements in technology have given us the tools to detect genetic defects associated with inherited cardiac conditions in as quick as __ days. It all starts with a quick and easy saliva swab collected from the patient which is then sent from the provider to our laboratory. We then isolate genomic DNA from the swab using the most widely trusted Thermo-Fisher DNA Extraction kit on the market. The individual’s DNA then undergoes a process known as Next Generation Sequencing. This revolutionary genomic technology allows us to sequence a patient’s DNA and target a broad coverage of cardiac genes with disease implications. Once sequenced, our team provides your medical provider with a comprehensive report about the patient’s genome highlighting all the genes associated with inherited heart diseases, and their genotype, to provide the most advanced level of patient care available.

CARDIOMYOPATHY

ABCC9 ACTC1 ACTN2 ANKRD1 BAG3 CRYAB CSRP3 DES DMD DOLK

DSC2 DSG2 DSP DTNA EYA4 GATAD1 LAMP2 LMNA MURC MYBPC3

MYH11 MYH6 MYH7 MYL2 MYL3 MYOZ2 PKP2 PLN PRKAG2 RYR2

SCN5A SGCD SLC25A4 TAZ TCAP TNNC1 TNNI3 TNNT2 TTN

CARDIO ARRHYTHMIA

ABCC9
CACNA1C CACNA2D1 CALM1
CASQ2
CAV3
GPD1L
HCN4
KCND3

KCNE2
KCNH2
KCNJ2
KCNJ8
KCNQ1
LMNA
MYH6
MNKX2-5
PRKAG2

RYR2
SCN1B
SCN2B
SCN3B
SCN4B
SCN5A

COMPREHENSIVE

ABCC9
ABCG5
ABCG8
ACTA1
ACTA2
ACTC1
ACTN2
AKAP9
ALMS1
ANK2
ANKRD1
APOA4
APOA5
APOB
APOC2
APOEBAG3
BRAF
CACNA1C CACNA2D1 CACNB2
CALM1
CALR3
CASQ2
CAV3
CBL
CBS

CETP
COL3A1
COL5A1
COL5A2
COX15
CREB3L3
CRELD1
CRYAB
CSRP3
CTF1
DES
DMD
DNAJC19
DOLK
DPP6
DSC2
DSG2
DSP
DTNA
EFEMP2
ELN
EMD
EYA4
FBN1
FBN2
FHL1
FHL2
FKRP
FKTN
FXN

GAA
GATAD1
GCKR
GJA5
GLA
GPD1L
GPIHBP1
HADHA
HCN4
HFE
HRAS
HSPB8
ILK
JAG1
JPH2
JUP
KCNA5
KCND3
KCNE1
KCNE2
KCNE3
KCNH2
KCNJ2
KCNJ5
KCNJ8
KCNQ1
KLF10
KRAS
LAMA2 

LAMA4
LAMP2
LDB3
LDLR
LDLRAP1
LMF1
LMNA
LPL
LTBP2
MAP2K1
MAP2K2
MIB1
MURC (CAVIN4)
MYBPC3
MYH11
MYH6
MYH7
MYL2
MYL3
MYLK
MYLK2
MYO6
MYOZ2
MYPN
NEXN
NKX2-5
NODAL
NOTCH1
NPPA

NRAS
PCSK9
PDLIM3
PKP2
PLN
PRDM16
PRKAG2 PRKAR1A
PTPN11
RAF1
RANGRF
RBM20
RYR1
RYR2
SALL4
SCN1B
SCN2B
SCN3B
SCN4B
SCN5A
SCO2
SDHA
SEPN1
SGCB
SGCD
SGCG
SHOC2
SLC25A4
SLC2A10

SMAD3
SMAD4
SNTA1
SOS1
SREBF2
TAZ
TBX20
TBX3
TBX5
TCAP
TGFB2
TGFB3
TGFBR1
TGFBR2
TMEM43
TMPO
TNNC1
TNNI3
TNNT2
TPM1
TRDN
TRIM63
TRPM4
TTN
TTR
TXNRD2
VCL
ZBTB17
ZHX3
ZIC3